Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 13/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628700 | 0.77 | S1PR1 (0.37) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL23628683 | 0.75 | S1PR1 (0.35) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL23628692 | 0.72 | IDO1 (0.41) | ARIDO1USP14 | |
| SCHEMBL31435375 | 0.71 | IDO1 (0.35) | IDO1USP14 | |
| SCHEMBL2502580 | 0.70 | IDO1 (0.38) | IDO1USP14 | |
| SCHEMBL21452000 | 0.70 | AR (0.49) | AR | |
| SCHEMBL2037857 | 0.69 | NOTUM (0.39) | ARS1PR1IDO1USP14 | |
| SCHEMBL17483413 | 0.69 | PDE10A (0.36) | — | |
| SCHEMBL18300556 | 0.68 | USP14 (0.33) | USP14 | |
| SCHEMBL18301283 | 0.68 | USP14 (0.33) | USP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847158-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | Arena Pharmaceuticals, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| CN-112955431-A | Compounds useful for the treatment of autoimmune and inflammatory disorders | 艾尼纳制药公司 | 2021-06-11 | — | — | CN | disclosed |