Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628683 | 0.80 | S1PR1 (0.35) | S1PR1S1PR4S1PR5ADORA3S1PR3 | |
| SCHEMBL23628681 | 0.80 | S1PR1 (0.38) | S1PR1S1PR4S1PR5ADORA3S1PR3 | |
| SCHEMBL23628679 | 0.78 | S1PR1 (0.38) | S1PR1S1PR4S1PR5ADORA3S1PR3 | |
| SCHEMBL23628696 | 0.77 | AR (0.35) | S1PR1S1PR4S1PR5S1PR3 | |
| SCHEMBL21452532 | 0.72 | AR (0.39) | — | |
| SCHEMBL23628692 | 0.71 | IDO1 (0.41) | — | |
| SCHEMBL2037857 | 0.68 | NOTUM (0.39) | S1PR1 | |
| SCHEMBL31435375 | 0.68 | IDO1 (0.35) | — | |
| SCHEMBL2502580 | 0.67 | IDO1 (0.38) | — | |
| SCHEMBL21451909 | 0.66 | GAA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847158-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | Arena Pharmaceuticals, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| CN-112955431-A | Compounds useful for the treatment of autoimmune and inflammatory disorders | 艾尼纳制药公司 | 2021-06-11 | — | — | CN | disclosed |