Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747751 | 0.85 | CD274 (0.43) | LIPGCSF1RDGAT1P4HBLPL | |
| SCHEMBL23575590 | 0.84 | USP30 (0.38) | CSF1RDGAT1HIF1ANR1I2 | |
| SCHEMBL19869980 | 0.83 | BRD9 (0.38) | LIPGCSF1RALDH1A1MEN1KMT2A | |
| SCHEMBL19747728 | 0.77 | AAK1 (0.37) | CSF1RDGAT1NR1I2 | |
| SCHEMBL23575287 | 0.77 | PTPN1 (0.44) | LIPGCSF1RDGAT1ALDH1A1MEN1 | |
| SCHEMBL20562111 | 0.76 | CA1 (0.44) | LIPGCSF1RDGAT1HPGDP4HB | |
| SCHEMBL23575186 | 0.75 | CD274 (0.43) | LIPGCSF1RDGAT1HIF1ANR1I2 | |
| SCHEMBL23121949 | 0.75 | PDE3B (0.45) | LIPGCSF1RDGAT1LPLHIF1A | |
| SCHEMBL1684669 | 0.75 | LIPG (0.53) | LIPGP4HBLPLF2F11 | |
| SCHEMBL1400888 | 0.74 | LIPG (0.36) | LIPGDGAT1P4HBLPLF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846800-A1 | COMPOUNDS FOR THE DEGRADATION OF BRD9 OR MTH1 | C4 Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |