Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326189 | 0.83 | CA12 (0.50) | TSHRLMNAHPGDALDH1A1KDM4E | |
| SCHEMBL31585831 | 0.83 | CA12 (0.50) | TSHRLMNAHPGDALDH1A1KDM4E | |
| SCHEMBL20757754 | 0.82 | AKR1C3 (0.62) | ALDH1A1KDM4EHSD17B10AKR1C3ATM | |
| SCHEMBL27840685 | 0.81 | TSHR (0.63) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL29363206 | 0.81 | TSHR (0.63) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL28000 | 0.81 | TSHR (0.63) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL8380470 | 0.81 | TSHR (0.50) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL235942 | 0.81 | MAPT (0.59) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| Benzophenone SCHEMBL29531226 | 0.80 | TSHR (0.61) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| Water SCHEMBL27735757 | 0.80 | TSHR (0.61) | TSHRMAPK1LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130035358-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SE) | 2013-02-07 | — | — | US | disclosed |
| EP-2545036-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | Biolipox AB (SE) | 2013-01-16 | — | — | EP | disclosed |
| CN-102348686-A | Bis aromatic compounds for use as ltc4 synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-08 | — | — | CN | disclosed |
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| WO-2011110824-A1 | BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS | BIOLIPOX AB (SE) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | TSHR 3028/4885MAPK1 2441/4885LMNA 759/4885 |
| US-20130035358-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | TSHR 3028/4885MAPK1 2441/4885LMNA 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.