Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.52 |
| ▸ | ASPH | Q12797 | 2/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.52 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.52 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL593292 | 0.89 | LMNA (0.56) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| 2-Picolinic Acid SCHEMBL593180 | 0.89 | LMNA (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL29951101 | 0.89 | KDM4E (0.63) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL65841 | 0.89 | KDM4E (0.63) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| Water SCHEMBL961425 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL593577 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| Bromide SCHEMBL9518799 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| SCHEMBL596161 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| 2-Picolinic Acid SCHEMBL594569 | 0.85 | LMNA (0.61) | KDM4EALDH1A1KDM5AKDM3AASPH | |
| 2-Picolinic Acid SCHEMBL593739 | 0.85 | LMNA (0.56) | KDM4EALDH1A1KDM5AKDM3AASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189781-A1 | DISTANCE-CONTROLLED ENERGY TRANSFER DYE COMPLEXES | BÜDDEFELD, JÜRGEN, PROF (DE) | 2011-08-04 | — | — | US | claimed |