Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Picolinic Acid SCHEMBL594569 | 0.97 | LMNA (0.61) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL12076591 | 0.97 | LMNA (0.61) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL593292 | 0.94 | LMNA (0.56) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL593739 | 0.91 | LMNA (0.56) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL2362971 | 0.89 | KDM4E (0.52) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL595042 | 0.87 | LMNA (0.69) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| 2-Picolinic Acid SCHEMBL593726 | 0.87 | LMNA (0.69) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL29951101 | 0.78 | KDM4E (0.63) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 | |
| 2-Picolinic Acid SCHEMBL28737738 | 0.78 | CES2 (0.64) | LMNAL3MBTL1NAPRTP4HTMCES2 | |
| SCHEMBL65841 | 0.78 | KDM4E (0.63) | LMNAL3MBTL1NAPRTP4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294159-B1 | DISTANCE-CONTROLLED ENERGY TRANSFER DYE COMPLEXES | INBIO PROF JUERGEN BUEDDEFELD DR PETER KLAUTH PROF MANFRED RIETZ GBR (DE) | 2012-09-05 | — | — | EP | claimed |
| US-20110189781-A1 | DISTANCE-CONTROLLED ENERGY TRANSFER DYE COMPLEXES | BÜDDEFELD, JÜRGEN, PROF (DE) | 2011-08-04 | — | — | US | claimed |
| EP-2294159-B1 | DISTANCE-CONTROLLED ENERGY TRANSFER DYE COMPLEXES | INBIO PROF JUERGEN BUEDDEFELD DR PETER KLAUTH PROF MANFRED RIETZ GBR (DE) | 2012-09-05 | — | — | EP | disclosed |
| EP-2417216-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | Inbio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz Gbr (DE) | 2012-02-15 | — | — | EP | disclosed |
| US-20110189781-A1 | DISTANCE-CONTROLLED ENERGY TRANSFER DYE COMPLEXES | BÜDDEFELD, JÜRGEN, PROF (DE) | 2011-08-04 | — | — | US | disclosed |
| WO-2010115503-A2 | MODIFICATION OF LAYERED SILICATES FOR LUMINESCENCE ACTIVATION | INBIO PROF. JÜRGEN BÜDDEFELD DR. PETER KLAUTH PROF. MANFRED RIETZ GBR (DE) | 2010-10-14 | — | — | WO | disclosed |