Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.55 |
| ▸ | MMP3 | P08254 | 7/20 | 0.55 |
| ▸ | MMP7 | P09237 | 6/20 | 0.55 |
| ▸ | MMP13 | P45452 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630316 | 0.99 | MMP1 (0.54) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630361 | 0.96 | MMP1 (0.51) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630312 | 0.84 | MMP1 (0.56) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630345 | 0.83 | MMP1 (0.58) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630432 | 0.82 | MMP1 (0.53) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630326 | 0.82 | MMP1 (0.59) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630341 | 0.82 | MMP1 (0.57) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630336 | 0.79 | MMP1 (0.53) | MMP1MMP3MMP7MMP13CA2 | |
| SCHEMBL23630483 | 0.79 | KMT2A (0.50) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20540954 | 0.75 | ALDH1A1 (0.56) | MMP1MMP3MMP7MMP13FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | claimed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | claimed |
| EP-4087651-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | UNIWERSYTET JAGIELLONSKI (PL) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141506-A1 | AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A1, THEIR SYNTHESIS AND USE | Uniwersytet Jagielloński (PL) | 2021-07-15 | — | — | WO | disclosed |