Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362335 | 0.84 | MAPT (0.64) | MAPTTP53POLBALDH1A1LMNA | |
| SCHEMBL2362551 | 0.82 | MAPT (0.56) | MAPTTP53POLBALDH1A1LMNA | |
| SCHEMBL2362570 | 0.79 | TP53 (0.64) | MAPTTP53POLBALDH1A1KMT2A | |
| SCHEMBL2355819 | 0.79 | MAPT (0.65) | MAPTTP53POLBALDH1A1LMNA | |
| SCHEMBL5636640 | 0.77 | TP53 (0.47) | TP53ALDH1A1 | |
| SCHEMBL18274592 | 0.76 | MAPT (0.51) | MAPTTP53POLBALDH1A1LMNA | |
| SCHEMBL12007580 | 0.75 | KDM4E (0.78) | MAPTTP53POLBALDH1A1KMT2A | |
| SCHEMBL16227646 | 0.74 | ALDH1A1 (0.69) | MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL2362291 | 0.74 | TP53 (0.66) | MAPTTP53POLBALDH1A1KMT2A | |
| SCHEMBL2363278 | 0.73 | MAPT (0.65) | MAPTTP53POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135672-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2017-03-01 | — | — | EP | claimed |
| EP-2356109-B1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2016-12-07 | — | — | EP | claimed |
| US-20110301149-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2011-12-08 | — | — | US | claimed |
| EP-2356109-A2 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2011-08-17 | — | — | EP | claimed |
| WO-2010042925-A2 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2010-04-15 | — | — | WO | claimed |
| EP-3135672-B9 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3135672-B9 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3135672-B1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3135672-B1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3135672-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-3135672-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2356109-B1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC (US) | 2016-12-07 | — | — | EP | disclosed |
| US-8729081-B2 | Compositions and methods for treating alcohol use disorders, pain and other diseases | VM DISCOVERY INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729081-B2 | Compositions and methods for treating alcohol use disorders, pain and other diseases | VM DISCOVERY INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20110301149-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301149-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301149-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2011-12-08 | — | — | US | disclosed |
| EP-2356109-A2 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010042925-A2 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042925-A2 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM DISCOVERY INC. (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301149-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | PRKCH, PRKCG, PRKCQ | MAPT 1539/4885TP53 4665/4885POLB 3613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.