Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202597 | 1.00 | ABCB1 (0.53) | ABCB1NR1H3PTPN1TAAR1TSHR | |
| SCHEMBL23202521 | 0.96 | PTPN1 (0.56) | ABCB1NR1H3PTPN1TAAR1TSHR | |
| SCHEMBL23202587 | 0.92 | TSHR (0.54) | NR1H3PTPN1TAAR1TSHRMAPK1 | |
| SCHEMBL30451526 | 0.92 | ABCB1 (0.61) | ABCB1NR1H3ABCG2CYP19A1ATM | |
| SCHEMBL23638842 | 0.92 | ABCB1 (0.61) | ABCB1NR1H3ABCG2CYP19A1ATM | |
| SCHEMBL23202589 | 0.91 | ABCB1 (0.54) | ABCB1NR1H3TSHRALOX5GABRA1 | |
| SCHEMBL23202582 | 0.91 | TUBB4A (0.52) | ABCB1NR1H3TSHRALOX5GABRA1 | |
| SCHEMBL23202596 | 0.85 | TUBB4A (0.55) | ABCB1NR1H3TSHRALOX5GABRA1 | |
| SCHEMBL31079358 | 0.85 | TUBB4A (0.55) | ABCB1NR1H3TSHRALOX5GABRA1 | |
| SCHEMBL8706804 | 0.81 | ABCB1 (0.64) | ABCB1NR1H3PTPN1ABCG2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805192-B1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | UNIV EWHA IND COLLABORATION (KR) | 2024-09-11 | — | — | EP | disclosed |
| US-11939308-B2 | Biphenyl derivative compound and use thereof | EWHA University—Industry Collaboration Foundation (KR) | 2024-03-26 | — | — | US | disclosed |
| US-20210214324-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-15 | — | — | US | disclosed |
| US-20210214324-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939308-B2 | Biphenyl derivative compound and use thereof | NDC1, NME1, NME4 | ABCB1 335/4885NR1H3 3424/4885PTPN1 1278/4885 |
| US-20210214324-A1 | Novel Biphenyl Derivative Compound and Use Thereof | NDC1, NME1, NUDC | ABCB1 281/4885NR1H3 3257/4885PTPN1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.