Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30361355 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2275702 | 0.76 | HTR2A (0.38) | — | |
| SCHEMBL30638591 | 0.74 | — | — | |
| SCHEMBL2363189 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL2272732 | 0.72 | CYP11B1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL30361401 | 0.72 | CYP11B1 (0.32) | — | |
| SCHEMBL28907323 | 0.70 | KDM4E (0.37) | — | |
| Hydrochloric Acid SCHEMBL2274495 | 0.70 | ACHE (0.41) | — | |
| SCHEMBL6759445 | 0.70 | HTR2A (0.39) | — | |
| SCHEMBL27638219 | 0.65 | HTR2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989564-B2 | Hafnocenes, zirconocenes; antistatic agents | UNIVATION TECHNOLOGIES, LLC (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080214753-A1 | Catalyst systems and their use in polymerization processes | UNIVATION TECHNOLOGIES, LLC (US) | 2008-09-04 | — | — | US | disclosed |
| US-7172816-B2 | High tear films from hafnocene catalyzed polyethylenes | UNIVATION TECHNOLOGIES, LLC (US) | 2007-02-06 | — | — | US | disclosed |
| US-20050215716-A1 | Such as bis(propylcyclopentadienyl) hafnium dichloride, film of given secant modulus, dart impact strength | SZUL JOHN F | 2005-09-29 | — | — | US | disclosed |