NDUFV3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL11456503	0.71	4/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8492845	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
SCHEMBL8494171	0.50	4/20
SCHEMBL8494175	0.50	4/20
SCHEMBL8494177	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20

Clinical trials — most relevant to NDUFV3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease	PHASE2	RECRUITING
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Nicotinamide Riboside in LVAD Recipients	EARLY_PHASE1	COMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
EPI-743 for Mitochondrial Respiratory Chain Diseases	nan	NO_LONGER_AVAILABLE
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells	nan	RECRUITING
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Mitoquines in COPD	nan	UNKNOWN
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFV3 binder may also engage these)

Protein	Name	Similarity
Q0MQJ0	—	1.000	Q0MQJ0 →
Q0MQJ2	—	1.000	Q0MQJ2 →
Q0MQJ1	—	1.000	Q0MQJ1 →
P25712	—	0.995	P25712 →
Q8BK30	—	0.988	Q8BK30 →
Q6PCU8	—	0.988	Q6PCU8 →
P82927	—	0.981	P82927 →
Q9Y6G3	—	0.979	Q9Y6G3 →
P0C2B7	—	0.978	P0C2B7 →
P0C2B9	—	0.976	P0C2B9 →
Q0MQJ3	—	0.976	Q0MQJ3 →
Q0MQJ4	—	0.975	Q0MQJ4 →
P82909	—	0.975	P82909 →
Q9CPV3	—	0.975	Q9CPV3 →
Q5R4S3	—	0.975	Q5R4S3 →
NDUFB11	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.974	landscape →
P82908	—	0.974	P82908 →
Q8HXG5	—	0.973	Q8HXG5 →
P83565	—	0.973	P83565 →
P0C2B8	—	0.973	P0C2B8 →
Q0MQJ5	—	0.972	Q0MQJ5 →
Q9Z2Q5	—	0.972	Q9Z2Q5 →
Q4V7Q1	—	0.972	Q4V7Q1 →
Q9NQ50	—	0.971	Q9NQ50 →
Q9DCJ7	—	0.971	Q9DCJ7 →
Q9D0Y8	—	0.971	Q9D0Y8 →
P82925	—	0.970	P82925 →
Q86TS9	—	0.970	Q86TS9 →
Q3MHJ5	—	0.969	Q3MHJ5 →
P82649	—	0.969	P82649 →