Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392115 | 0.82 | SLC6A4 (0.43) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL13162567 | 0.81 | NOS3 (0.33) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5572628 | 0.79 | NOS3 (0.38) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL24778488 | 0.78 | — | — | |
| SCHEMBL23634801 | 0.77 | PIK3CD (0.48) | — | |
| SCHEMBL16854657 | 0.77 | SLC6A4 (0.37) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL23634822 | 0.76 | KDM4E (0.38) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL1088444 | 0.76 | SLC6A2 (0.43) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL1829058 | 0.75 | SLC6A4 (0.40) | NOS3NOS1NOS2SLC6A2SLC6A4 | |
| SCHEMBL3015437 | 0.75 | NOS3 (0.36) | NOS3NOS1NOS2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |