Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13209132 | 0.82 | PIK3CD (0.50) | PIK3CDALDH1A1NPC1RAB9A | |
| SCHEMBL24778488 | 0.78 | — | — | |
| SCHEMBL23634795 | 0.77 | NOS3 (0.33) | — | |
| SCHEMBL23634822 | 0.76 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL18248982 | 0.74 | PIK3CD (0.53) | PIK3CDALDH1A1NPC1RAB9A | |
| SCHEMBL13209130 | 0.74 | PIK3CD (0.53) | PIK3CDALDH1A1NPC1RAB9A | |
| SCHEMBL11938911 | 0.72 | PIK3CD (0.52) | PIK3CDALDH1A1NPC1RAB9A | |
| SCHEMBL29731031 | 0.72 | LTA4H (0.47) | ALDH1A1NPC1RAB9A | |
| SCHEMBL29731012 | 0.71 | TSHR (0.44) | ALDH1A1 | |
| SCHEMBL24976959 | 0.71 | PIK3CD (0.50) | PIK3CDALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |