Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 16/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012078 | 0.79 | KDM4E (0.39) | OPRL1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23634793 | 0.78 | KDM4E (0.45) | KDM4ECYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3427369 | 0.76 | OPRL1 (0.38) | OPRL1 | |
| SCHEMBL19966122 | 0.74 | OPRL1 (0.37) | OPRL1 | |
| SCHEMBL13856214 | 0.73 | SMN1; SMN2 (0.36) | OPRL1KDM4EALDH1A1 | |
| SCHEMBL3431504 | 0.72 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL4973433 | 0.72 | L3MBTL1 (0.38) | OPRL1KDM4ECYP2C19ALDH1A1 | |
| SCHEMBL20160787 | 0.71 | OPRL1 (0.39) | OPRL1 | |
| SCHEMBL375142 | 0.71 | OPRL1 (0.39) | OPRL1 | |
| SCHEMBL1794700 | 0.71 | OPRL1 (0.41) | OPRL1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |