Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84801 | 0.84 | ALDH1A1 (0.51) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL8221324 | 0.82 | ALDH1A1 (0.48) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL1100792 | 0.81 | KDM1A (0.43) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL4508386 | 0.79 | KDM1A (0.42) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL12793973 | 0.79 | HRH2 (0.47) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL14670865 | 0.77 | PTGS2 (0.54) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL14041545 | 0.77 | HRH3 (0.45) | HRH3KDM4EALDH1A1 | |
| SCHEMBL1098206 | 0.77 | KDM1A (0.45) | HRH2HRH1KDM1AKDM4EALDH1A1 | |
| SCHEMBL15295188 | 0.76 | HRH2 (0.44) | HRH2HRH1HRH3KDM1AKDM4E | |
| SCHEMBL12137190 | 0.76 | ALDH1A1 (0.49) | HRH2HRH1HRH3KDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |