Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190262 | 0.85 | ALDH1A1 (0.50) | FABP6TP53ALDH1A1OPRL1GSK3B | |
| SCHEMBL14400085 | 0.80 | FABP6 (0.49) | FABP6TP53ALDH1A1OPRL1EPHX2 | |
| SCHEMBL6976860 | 0.78 | TP53 (0.41) | FABP6TP53ALDH1A1OPRL1EPHX2 | |
| SCHEMBL12750868 | 0.75 | FABP6 (0.51) | FABP6TP53ALDH1A1OPRL1EPHX2 | |
| SCHEMBL23634806 | 0.74 | EPHX2 (0.45) | ALDH1A1OPRL1EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL477233 | 0.73 | FABP6 (0.44) | FABP6TP53ALDH1A1OPRL1EPHX2 | |
| SCHEMBL23640236 | 0.72 | ALDH1A1 (0.48) | FABP6ALDH1A1OPRL1HTTSMN1; SMN2 | |
| SCHEMBL12820051 | 0.71 | TP53 (0.48) | FABP6TP53ALDH1A1EPHX2KDM1A | |
| SCHEMBL16127663 | 0.70 | TP53 (0.44) | FABP6TP53ALDH1A1NPSR1HTT | |
| SCHEMBL17778089 | 0.70 | FABP6 (0.61) | FABP6TP53ALDH1A1OPRL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |