Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.39 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634808 | 0.90 | NUAK1 (0.42) | CRBNNUAK1DDB1POLBGAA | |
| SCHEMBL23634853 | 0.90 | NUAK1 (0.42) | CRBNNUAK1DDB1POLBGAA | |
| SCHEMBL23634844 | 0.90 | NUAK1 (0.42) | CRBNNUAK1DDB1POLBGAA | |
| SCHEMBL23635011 | 0.87 | CRBN (0.42) | CRBNNUAK1DDB1POLBKMT2A | |
| SCHEMBL23634906 | 0.87 | CRBN (0.42) | CRBNNUAK1DDB1POLBKMT2A | |
| SCHEMBL23635013 | 0.87 | CRBN (0.42) | CRBNNUAK1DDB1POLBKMT2A | |
| SCHEMBL23634893 | 0.86 | CRBN (0.43) | CRBNDDB1POLBGAAKMT2A | |
| SCHEMBL23634910 | 0.86 | MAOA (0.46) | CRBNDDB1SIGMAR1HRH3MAOA | |
| SCHEMBL23634902 | 0.85 | PDE3B (0.41) | CRBNKMT2A | |
| SCHEMBL23635033 | 0.85 | CRBN (0.40) | CRBNDDB1POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |