Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189015 | 0.87 | USP2 (0.46) | USP2SMN1; SMN2CTSKGPR119MEN1 | |
| SCHEMBL698803 | 0.74 | USP2 (0.69) | USP2SMN1; SMN2GPR119MEN1KMT2A | |
| SCHEMBL18294 | 0.74 | USP2 (0.69) | USP2SMN1; SMN2GPR119MEN1KMT2A | |
| SCHEMBL12615141 | 0.73 | USP2 (0.42) | USP2SMN1; SMN2CTSKGPR119MEN1 | |
| SCHEMBL23635372 | 0.73 | HPGD (0.52) | GPR119MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16370880 | 0.72 | USP2 (0.44) | USP2SMN1; SMN2CTSKGPR119MEN1 | |
| SCHEMBL16825742 | 0.72 | ALDH1A1 (0.65) | USP2SMN1; SMN2CTSKMEN1KMT2A | |
| SCHEMBL15863855 | 0.72 | USP2 (0.44) | USP2SMN1; SMN2CTSKGPR119MEN1 | |
| SCHEMBL12697881 | 0.72 | USP2 (0.44) | USP2SMN1; SMN2CTSKGPR119MEN1 | |
| SCHEMBL16846230 | 0.72 | ALDH1A1 (0.65) | USP2SMN1; SMN2CTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142420-A1 | PYRAZOLO[1,5-a]PYRIMIDIN-7(4H)-ONE INHIBITORS OF DYNEIN | KAPOOR TARUN M (US) | 2021-07-15 | — | — | WO | disclosed |