Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961270 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL23635688 | 0.77 | KDM1A (0.41) | KDM4EMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL23645214 | 0.74 | LGMN (0.53) | SMN1; SMN2KDM4EMEN1KMT2AKDM1A | |
| SCHEMBL24703554 | 0.71 | KDM4E (0.57) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL14123262 | 0.71 | KDM4E (0.49) | SMN1; SMN2KDM4EMEN1CYP2C9CYP2C19 | |
| SCHEMBL7340852 | 0.70 | KDM4E (0.52) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL23644930 | 0.67 | LGMN (0.50) | KDM4EMEN1KMT2ANPSR1KDM1A | |
| SCHEMBL29251528 | 0.66 | APEX1 (0.53) | KDM4EKMT2AKDM1AALDH1A1HPGD | |
| SCHEMBL11045234 | 0.65 | GRIK1 (0.45) | SMN1; SMN2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL18989707 | 0.65 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |
| WO-2021139498-A1 | ISOXAZOLINE OXIME CARBOXYLATE COMPOUND, PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-15 | — | — | WO | disclosed |
| WO-2021139482-A1 | CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-15 | — | — | WO | disclosed |