SCHEMBL23635692

SCHEMBL23635692

CCOC(=O)c1ocnc1COC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
TSHR P16473 1/20 0.36
PDE4D Q08499 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567865 0.85 CYP1A2 (0.40) CA12CA1CA2CA7CA9
SCHEMBL13545979 0.83 PLK1 (0.43) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL28816669 0.80 PLK1 (0.39) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL2139059 0.78 ALDH1A1 (0.48) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL29620241 0.77 KDM4E (0.41) CYP1A2CYP2C9CYP2C19TSHRALDH1A1
SCHEMBL25368994 0.77 CYP1A2 (0.41) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL21854494 0.76 GLP1R (0.46) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL3714376 0.76 CYP1A2 (0.40) CA12CA1CA2CA7CA9
SCHEMBL21854511 0.73 ALDH1A1 (0.42) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL22952394 0.73 ALDH1A1 (0.43) L3MBTL1CYP1A2CYP2C9CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed