Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545979 | 0.88 | PLK1 (0.43) | PLK1HSP90AA1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL2567865 | 0.84 | CYP1A2 (0.40) | HSP90AA1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23635692 | 0.80 | CA12 (0.38) | L3MBTL1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3714376 | 0.78 | CYP1A2 (0.40) | PLK1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2139059 | 0.77 | ALDH1A1 (0.48) | L3MBTL1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29620241 | 0.76 | KDM4E (0.41) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL25368994 | 0.76 | CYP1A2 (0.41) | L3MBTL1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL22952394 | 0.75 | ALDH1A1 (0.43) | HSP90AA1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21854494 | 0.75 | GLP1R (0.46) | L3MBTL1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15919895 | 0.74 | KDM4E (0.49) | HSP90AA1CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630822-A | Biaryl dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-06-14 | — | — | CN | disclosed |