SCHEMBL23635696

SCHEMBL23635696

COCc1ccc(Cl)c(OC)c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 2/20 0.50
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35
TUBB6 Q9BUF5 1/20 0.35
TUBB2B Q9BVA1 1/20 0.35
TUBB1 Q9H4B7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948911 0.83 MEP1B (0.55) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL15791896 0.81 MEP1B (0.50) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL4651909 0.81 MEP1B (0.54) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL19251350 0.81 MEP1B (0.48) MEP1BALDH1A1KDM4ETUBB4ATUBB
SCHEMBL13547949 0.79 MEP1B (0.48) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL13548278 0.79 MEP1B (0.48) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL19072856 0.79 MEP1B (0.51) MEP1BHTR2A
SCHEMBL15774308 0.79 MEP1B (0.48) MEP1BALDH1A1KDM4EHSD17B10TSHR
SCHEMBL22768370 0.78 ALOX5AP (0.42) MEP1BALDH1A1TSHRTUBB1HTR2A
SCHEMBL18244619 0.76 ALDH1A1 (0.45) MEP1BALDH1A1KDM4EHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed