Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842110 | 1.00 | NPC1 (0.49) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL23292567 | 0.85 | NPC1 (0.54) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL27097771 | 0.84 | KDM4E (0.56) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL23635946 | 0.84 | KDM4E (0.55) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL27097742 | 0.76 | KDM4E (0.58) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL23635873 | 0.74 | KDM4E (0.54) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL23292543 | 0.73 | DYRK1A (0.41) | NPC1ALDH1A1HPGDRXFP1KDM4E | |
| SCHEMBL23292540 | 0.73 | KDM4E (0.54) | NPC1ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL27879248 | 0.72 | SMN1; SMN2 (0.61) | NPC1ALDH1A1HPGDRAB9AKMT2A | |
| SCHEMBL30842121 | 0.71 | KDM4E (0.53) | NPC1ALDH1A1HPGDKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-11911372-B2 | Compounds | CTXT PTY LTD (AU) | 2024-02-27 | — | — | US | disclosed |
| US-20210213004-A1 | Compounds | CTXT PTY LTD (AU) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213004-A1 | Compounds | SLC10A1, ABCB11, REN | NPC1 13/4885ALDH1A1 744/4885HPGD 1882/4885 |
| US-11911372-B2 | Compounds | SLC10A1, ABCB11, REN | NPC1 13/4885ALDH1A1 744/4885HPGD 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.