Diphenylether

Diphenylether

SCHEMBL23636264

C=CCOC(=C)c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
LTA4H P09960 3/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
PGR P06401 1/20 0.40
ALDH1A1 P00352 3/20 0.40
AKR1C3 P42330 1/20 0.40
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
TGM2 P21980 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PKM P14618 1/20 0.38
CASP1 P29466 1/20 0.37
PARP10 Q53GL7 1/20 0.37
MMP9 P14780 1/20 0.37
SRD5A2 P31213 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7898616 0.91 CYP3A4 (0.50) CYP3A4TSHRSMN1; SMN2GAAALDH1A1
SCHEMBL11054303 0.77 SMN1; SMN2 (0.60) CYP3A4TSHRSMN1; SMN2GAAGLA
SCHEMBL23636268 0.76 ALDH1A1 (0.43) TSHRSMN1; SMN2RAB9AALDH1A1HSD17B10
Diphenylether SCHEMBL11667270 0.75 LTA4H (0.55) CYP3A4LTA4HTSHRSMN1; SMN2GAA
SCHEMBL6118207 0.74 CYP3A4 (0.52) CYP3A4TSHRSMN1; SMN2GAAALDH1A1
SCHEMBL11865429 0.72 ERCC5 (0.57) CYP3A4SMN1; SMN2GAAGLAHTT
SCHEMBL5973615 0.72 LTA4H (0.55) LTA4HTSHRSMN1; SMN2GAAGLA
SCHEMBL11648427 0.71 SRD5A2 (0.51) CYP3A4LTA4HSMN1; SMN2GAAGLA
Diphenylether SCHEMBL27491160 0.71 LTA4H (0.60) LTA4HTSHRPGRAKR1C3NR1H2
SCHEMBL8423603 0.71 CYP3A4 (0.48) CYP3A4TSHRSMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11069856-B2 Solution for organic EL, method of producing organic EL device and organic EL device JOLED INC. (JP) 2021-07-20 US claimed