Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.52 |
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23632655 | 1.00 | RORC (0.52) | RORCACACBMAPK14TP53THRB | |
| SCHEMBL23642189 | 0.93 | RORC (0.53) | RORCACACBMAPK14TP53THRB | |
| SCHEMBL23636805 | 0.89 | PRKAA2 (0.51) | RORCACACB | |
| SCHEMBL23636965 | 0.89 | MEN1 (0.52) | ACACBMAPK14 | |
| SCHEMBL23636728 | 0.89 | DGAT2 (0.51) | RORCACACB | |
| SCHEMBL23636666 | 0.86 | ACACB (0.47) | ACACBMAPK14 | |
| SCHEMBL21619482 | 0.85 | RORC (0.55) | RORC | |
| SCHEMBL21619519 | 0.85 | RORC (0.55) | RORC | |
| SCHEMBL23632415 | 0.85 | RORC (0.53) | RORC | |
| SCHEMBL23636932 | 0.85 | RORC (0.49) | RORCMAPK14TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |