Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467600 | 0.83 | HTT (0.43) | LMNAHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL20889112 | 0.75 | HTT (0.51) | LMNAHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL25737357 | 0.74 | LMNA (0.31) | LMNAHTT | |
| SCHEMBL22570643 | 0.71 | THRA (0.48) | LMNATSHRPDE4BSMN1; SMN2MEN1 | |
| SCHEMBL3347697 | 0.71 | SCN9A (0.35) | LMNATSHRALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22556835 | 0.70 | THRA (0.47) | LMNATSHRPDE4BSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL29392777 | 0.70 | THRA (0.47) | LMNATSHRPDE4BSMN1; SMN2MEN1 | |
| SCHEMBL9495275 | 0.70 | PARP1 (0.45) | LMNAHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL20098896 | 0.70 | TSHR (0.53) | LMNAHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL22556768 | 0.69 | MRGPRX4 (0.53) | LMNATSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848366-A1 | HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |