SCHEMBL23637312

SCHEMBL23637312

Clc1cc(C2(c3ccccc3)c3ccccc3-c3c2ccc2ccccc32)cc2c1sc1ccccc12

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.34
TYMS P04818 1/20 0.34
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
NQO1 P15559 1/20 0.32
NQO2 P16083 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637487 0.88 KDM4E (0.36) MAPT
SCHEMBL23637498 0.82 CYP1A1 (0.34) DHFRTYMSCYP1A1CYP1B1MAPT
SCHEMBL23637491 0.80 KDM4E (0.34) DHFRTYMSMAPT
SCHEMBL29557713 0.79 MAPT (0.42) DHFRTYMSCYP1B1MAPT
SCHEMBL15676320 0.79 MAPT (0.42) DHFRTYMSCYP1B1MAPT
SCHEMBL23637492 0.77 CYP1A1 (0.43) DHFRTYMSCYP1A1CYP1B1NQO1
SCHEMBL20127213 0.76 SLC6A3 (0.42) DHFRTYMSMAPT
SCHEMBL23637500 0.76 KDM4E (0.35) MAPT
SCHEMBL18926896 0.76 NQO1 (0.34) DHFRTYMSCYP1A1CYP1B1NQO1
SCHEMBL23637435 0.75 ALOX5 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed