SCHEMBL23637460

SCHEMBL23637460

c1ccc2c(c1)Sc1ccc(Nc3ccc(-c4ccc5ccccc5c4)cc3)cc1C21c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PDK2 Q15119 2/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
PTGES O14684 1/20 0.34
GAA P10253 1/20 0.34
VCP P55072 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24723407 0.92 ALDH1A1 (0.36) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL23637457 0.89 PDK2 (0.43) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL24723470 0.88 ALDH1A1 (0.36) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL16017142 0.86 ALDH1A1 (0.47) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL24723597 0.85 PDK2 (0.40) ALDH1A1PDK2MEN1KMT2AMAPT
SCHEMBL22891473 0.85 PDK2 (0.49) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL22891731 0.84 ALDH1A1 (0.45) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL22891421 0.83 PDK2 (0.48) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL23637465 0.82 ALDH1A1 (0.33) ALDH1A1HPGDCYP3A4HSD17B10PDK2
SCHEMBL24723468 0.82 ALDH1A1 (0.34) ALDH1A1HPGDCYP3A4HSD17B10PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed