SCHEMBL23637465

SCHEMBL23637465

c1ccc(-c2ccc(Nc3ccc4c(c3)C3(c5ccccc5S4)c4ccccc4-c4c3ccc3ccccc43)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
PDK2 Q15119 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24723468 0.97 ALDH1A1 (0.34) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL23637457 0.85 PDK2 (0.43) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL23307857 0.83 PDK2 (0.30) PDK2
SCHEMBL23637460 0.82 ALDH1A1 (0.40) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL22305451 0.82 DNMT1 (0.37) ALDH1A1MAPTHSD17B10
SCHEMBL24723407 0.81 ALDH1A1 (0.36) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL18311931 0.81 PDK2 (0.47) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL31114615 0.81 PDK2 (0.47) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL22891733 0.81 PDK2 (0.40) ALDH1A1MAPTPDK2CYP3A4HPGD
SCHEMBL24723597 0.80 PDK2 (0.40) ALDH1A1MAPTPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141356-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-07-15 WO disclosed