Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489364 | 0.95 | ELANE (0.53) | ELANES100A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL22353034 | 0.85 | ELANE (0.51) | ELANES100A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16939667 | 0.84 | KMT2A (0.43) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL22345623 | 0.81 | ELANE (0.49) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4642778 | 0.81 | MAPT (0.61) | ELANES100A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17717380 | 0.80 | ELANE (0.49) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL22352933 | 0.80 | ELANE (0.47) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| Anthraquinone SCHEMBL17448113 | 0.79 | ELANE (0.56) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL15085173 | 0.79 | MAPT (0.62) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| Hydrogen Sulfide SCHEMBL27822874 | 0.79 | ELANE (0.55) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214297-A1 | METHOD FOR PREPARING KETO-FUNCTIONALIZED AROMATIC (METH)ACRYLATES | EVONIK OPERATIONS GMBH (DE) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214297-A1 | METHOD FOR PREPARING KETO-FUNCTIONALIZED AROMATIC (METH)ACRYLATES | ALKBH3, ALKBH5, ACR | ELANE 4235/4885S100A4 2508/4885MAPT 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.