SCHEMBL23637669

SCHEMBL23637669

c1ccc(CCN2CCOCC2)cc#1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.51
POLB P06746 1/20 0.46
L3MBTL3 Q96JM7 1/20 0.46
HRH3 Q9Y5N1 2/20 0.40
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
SLC6A3 Q01959 1/20 0.37
CNR1 P21554 1/20 0.37
HTR1A P08908 1/20 0.37
DRD2 P14416 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
HTR2A P28223 1/20 0.36
MAPK1 P28482 1/20 0.36
SCN1A P35498 1/20 0.36
HTR2B P41595 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422200 0.81 SIGMAR1 (0.56) SIGMAR1POLBL3MBTL3HRH3KMT2A
SCHEMBL5395459 0.79 SIGMAR1 (0.53) SIGMAR1POLBL3MBTL3KMT2AMEN1
SCHEMBL3186832 0.73 SIGMAR1 (0.55) SIGMAR1POLBL3MBTL3HRH3CYP1A2
SCHEMBL3176117 0.73 SIGMAR1 (0.63) SIGMAR1POLBL3MBTL3ALDH1A1CYP1A2
SCHEMBL9539677 0.73 SIGMAR1 (0.79) SIGMAR1POLBKMT2AMEN1HTT
SCHEMBL78043 0.73 SIGMAR1 (0.79) SIGMAR1POLBKMT2AMEN1HTT
SCHEMBL3135711 0.72 HRH3 (0.54) SIGMAR1POLBL3MBTL3HRH3KMT2A
SCHEMBL998374 0.71 SIGMAR1 (0.70) SIGMAR1POLBL3MBTL3HRH3KMT2A
SCHEMBL23235098 0.70 SIGMAR1 (0.60) SIGMAR1POLBL3MBTL3HRH3KMT2A
SCHEMBL24022514 0.70 SIGMAR1 (0.60) SIGMAR1POLBL3MBTL3HRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141165-A1 AMINO ALCOHOL-BORON-BINOL COMPOSITE AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE USING SAME (주)분자와물질 2021-07-15 WO disclosed