SCHEMBL23638201

SCHEMBL23638201

CC(C)C[C@H](NC(=O)c1ccccc1N=[N+]=[N-])C(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2R P25116 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CLPP Q16740 2/20 0.39
GAA P10253 1/20 0.38
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
TAS1R3 Q7RTX0 7/20 0.37
TAS1R1 Q7RTX1 7/20 0.37
ATM Q13315 1/20 0.37
PSMB5 P28074 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24344552 1.00 F2R (0.40) F2RTDP1CLPPGAACNR1
SCHEMBL25840835 0.95 GAA (0.37) F2RTDP1CLPPGAACNR1
SCHEMBL22493181 0.87 F2R (0.42) F2RTDP1CNR1CNR2
SCHEMBL22468823 0.87 F2R (0.42) F2RTDP1CNR1CNR2
SCHEMBL23638346 0.83 MAPT (0.47) TDP1GAACNR2ATM
SCHEMBL23638343 0.82 GRN (0.46) F2RCLPP
SCHEMBL23875438 0.82 F2R (0.41) F2RTDP1CLPPPSMB5
SCHEMBL23638202 0.80 ALDH1A1 (0.47) TDP1CLPPGAACNR1CNR2
SCHEMBL24344012 0.80 ALDH1A1 (0.47) TDP1CLPPGAACNR1CNR2
SCHEMBL23631770 0.76 F2R (0.44) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US disclosed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US disclosed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US disclosed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US disclosed
US-20230021091-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-01-19 US disclosed
WO-2022072560-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2022-04-07 WO disclosed
US-20210214701-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-07-15 US disclosed