SCHEMBL25840835

SCHEMBL25840835

Cc1c(F)c(F)c(F)c(OC(=O)[C@H](CC(C)C)NC(=O)c2ccccc2N=[N+]=[N-])c1F

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
F2R P25116 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.36
CLPP Q16740 2/20 0.36
TAS1R3 Q7RTX0 8/20 0.35
TAS1R1 Q7RTX1 8/20 0.35
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23638201 0.95 F2R (0.40) GAAF2RTDP1SMN1; SMN2ATM
SCHEMBL24344552 0.95 F2R (0.40) GAAF2RTDP1SMN1; SMN2ATM
SCHEMBL22468823 0.83 F2R (0.42) F2RTDP1CNR1CNR2
SCHEMBL22493181 0.83 F2R (0.42) F2RTDP1CNR1CNR2
SCHEMBL23638346 0.79 MAPT (0.47) GAATDP1ATMCNR2
SCHEMBL23638343 0.78 GRN (0.46) F2RCLPP
SCHEMBL23875438 0.78 F2R (0.41) F2RTDP1CLPP
SCHEMBL24344012 0.76 ALDH1A1 (0.47) GAATDP1SMN1; SMN2ATMCLPP
SCHEMBL23638202 0.76 ALDH1A1 (0.47) GAATDP1SMN1; SMN2ATMCLPP
SCHEMBL23631770 0.72 F2R (0.44) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US disclosed