Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363953 | 0.76 | MEN1 (0.41) | CSNK1EMEN1KMT2A | |
| Hydrogen Peroxide SCHEMBL9456660 | 0.73 | ALDH1A1 (0.46) | CSNK1EALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL11411634 | 0.71 | MEN1 (0.45) | CSNK1EALDH1A1SPHK1SPHK2MEN1 | |
| SCHEMBL7616178 | 0.71 | ALDH1A1 (0.43) | CSNK1EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27556298 | 0.70 | CSNK1E (0.38) | CSNK1EALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL20717915 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL12605621 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL27517561 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL12605622 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL8666513 | 0.69 | CSNK1E (0.42) | CSNK1EALDH1A1ASAH1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |