Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363899 | 0.76 | CSNK1E (0.39) | MEN1KMT2ACSNK1E | |
| SCHEMBL28894093 | 0.73 | MEN1 (0.51) | MEN1KMT2AATMSIGMAR1GAA | |
| SCHEMBL11299786 | 0.72 | MEN1 (0.39) | MEN1KMT2AGAAMAPK1MBOAT4 | |
| SCHEMBL8979455 | 0.72 | MEN1 (0.36) | MEN1KMT2AATMSIGMAR1GAA | |
| SCHEMBL31651201 | 0.72 | TNNC1 (0.42) | SIGMAR1CSNK1E | |
| SCHEMBL6471777 | 0.72 | SIGMAR1 (0.46) | MEN1KMT2AATMSIGMAR1GAA | |
| SCHEMBL3422456 | 0.72 | SIGMAR1 (0.46) | MEN1KMT2ASIGMAR1GAASCN5A | |
| SCHEMBL3809940 | 0.72 | SIGMAR1 (0.46) | MEN1KMT2ASIGMAR1GAASCN5A | |
| SCHEMBL11413546 | 0.72 | SIGMAR1 (0.64) | SIGMAR1GAASCN5ASCN9AMAPK1 | |
| SCHEMBL9782412 | 0.72 | SIGMAR1 (0.46) | MEN1KMT2AATMSIGMAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |