Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547309 | 0.82 | TLR8 (0.48) | ALDH1A1NPC1HCAR3 | |
| SCHEMBL15223284 | 0.79 | NCF1 (0.53) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL14237602 | 0.78 | FABP1 (0.57) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL169871 | 0.78 | SLC2A1 (0.47) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL13324092 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11486599 | 0.76 | KDM4E (0.51) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL18193668 | 0.76 | POLB (0.50) | POLBALDH1A1KDM4ENPC1GRM5 | |
| SCHEMBL1602180 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL13324076 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28064480 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141041-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | 大日本住友製薬株式会社 | 2021-07-15 | — | — | WO | disclosed |