Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055612 | 0.84 | NR1I2 (0.31) | NR1I2KCNH2GRM2F2F10 | |
| SCHEMBL23055252 | 0.76 | KMT2A (0.38) | KCNH2 | |
| SCHEMBL23639070 | 0.74 | MAPT (0.37) | CCNT1F2F10F7F3 | |
| SCHEMBL23639047 | 0.70 | KMT2A (0.42) | F2F10F7F3 | |
| SCHEMBL23055607 | 0.69 | GRM2 (0.33) | NR1I2KCNH2GRM2 | |
| SCHEMBL23639064 | 0.67 | STK17B (0.47) | CCNT1F2F10F7F3 | |
| SCHEMBL24782854 | 0.67 | HRH3 (0.33) | — | |
| SCHEMBL23639160 | 0.67 | MAPKAPK2 (0.36) | CCNT1F2F10F7F3 | |
| SCHEMBL23639175 | 0.65 | CKS1B (0.40) | — | |
| SCHEMBL23055334 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021141041-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | 大日本住友製薬株式会社 | 2021-07-15 | — | — | WO | disclosed |