SCHEMBL23055252 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.38

▸	MAP4K4	O95819	4/20	0.36

▸	OGA	O60502	2/20	0.35

▸	CKS1B	P61024	2/20	0.35

▸	SKP1	P63208	2/20	0.35

▸	SKP2	Q13309	2/20	0.35

▸	GPR119	Q8TDV5	2/20	0.35

▸	GBA1	P04062	1/20	0.35

▸	NPC1	O15118	2/20	0.34

▸	RAB9A	P51151	2/20	0.34

▸	MAPT	P10636	3/20	0.34

▸	HRH3	Q9Y5N1	2/20	0.34

▸	KCNH2	Q12809	1/20	0.34

▸	MEN1	O00255	1/20	0.34

▸	RXFP1	Q9HBX9	1/20	0.34

▸	TP53	P04637	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23639047	0.84	KMT2A (0.42)	KMT2ACKS1BSKP1SKP2GPR119
SCHEMBL23639175	0.83	CKS1B (0.40)	KMT2ACKS1BSKP1SKP2GPR119
SCHEMBL23639251	0.79	OGA (0.38)	KMT2AMAP4K4OGAGBA1NPC1
SCHEMBL23639070	0.76	MAPT (0.37)	KMT2ANPC1RAB9AMAPTMEN1
SCHEMBL23639167	0.76	CCNT1 (0.31)	KCNH2
SCHEMBL23639064	0.69	STK17B (0.47)	MAPT
SCHEMBL24784245	0.69	RET (0.34)	CKS1BSKP1SKP2
SCHEMBL23639160	0.69	MAPKAPK2 (0.36)	GPR119
SCHEMBL23055250	0.68	GPR119 (0.38)	MAP4K4CKS1BSKP1SKP2GPR119
SCHEMBL31330664	0.64	NPC1 (0.46)	KMT2AGPR119NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021039961-A1	RING-FUSED PYRAZOLE DERIVATIVE	大日本住友製薬株式会社	2021-03-04	—	—	WO	disclosed