Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055612 | 0.80 | NR1I2 (0.31) | TRPV1 | |
| SCHEMBL23697930 | 0.68 | HDAC6 (0.35) | HRH3 | |
| SCHEMBL23055589 | 0.68 | BRD4 (0.39) | — | |
| SCHEMBL23639167 | 0.67 | CCNT1 (0.31) | — | |
| SCHEMBL11858021 | 0.65 | HRH3 (0.43) | HRH3 | |
| SCHEMBL18573832 | 0.64 | LOXL2 (0.42) | — | |
| SCHEMBL11197977 | 0.64 | ESR2 (0.44) | HRH3BACE1 | |
| SCHEMBL10932787 | 0.63 | HSD17B10 (0.45) | BACE1 | |
| SCHEMBL23697919 | 0.63 | KDM4E (0.35) | — | |
| SCHEMBL10931097 | 0.63 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |