Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055252 | 0.79 | KMT2A (0.38) | OGAKCNH2HRH3MEN1KMT2A | |
| SCHEMBL24784431 | 0.63 | MAPT (0.40) | OGAKCNH2HRH3ADRA2BADRA2C | |
| SCHEMBL27914111 | 0.63 | ALDH1A1 (0.44) | OGAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23432729 | 0.62 | HRH3 (0.42) | HRH3HTR2CALDH1A1MEN1KMT2A | |
| SCHEMBL17481378 | 0.61 | HRH4 (0.40) | OGAKCNH2HRH3MEN1KMT2A | |
| SCHEMBL23602749 | 0.61 | HRH3 (0.55) | KCNH2HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL12302240 | 0.60 | ALDH1A1 (0.56) | KCNH2HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL17481374 | 0.59 | MAPT (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6628400 | 0.59 | MAPT (0.45) | OGAHRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL25188971 | 0.59 | MEN1 (0.47) | OGAKCNH2HRH3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021141041-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | 大日本住友製薬株式会社 | 2021-07-15 | — | — | WO | disclosed |