Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676748 | 0.89 | L3MBTL1 (0.37) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL23639678 | 0.89 | L3MBTL1 (0.41) | L3MBTL1CYP2A6CSNK1A1CSNK1DGSK3B | |
| SCHEMBL898346 | 0.88 | L3MBTL1 (0.36) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31540875 | 0.88 | L3MBTL1 (0.36) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31507391 | 0.83 | L3MBTL1 (0.37) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31540879 | 0.82 | CDK2 (0.32) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL24676630 | 0.80 | L3MBTL1 (0.38) | L3MBTL1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL898010 | 0.79 | L3MBTL1 (0.36) | L3MBTL1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL28351222 | 0.78 | L3MBTL1 (0.36) | L3MBTL1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL18056817 | 0.77 | ALK (0.52) | CSNK1G2ALKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848361-A1 | METHOD OF PRODUCING TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-07-14 | — | — | EP | disclosed |