Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897560 | 0.86 | MTNR1A (0.40) | CACNA1BMTNR1AMTNR1B | |
| SCHEMBL31507377 | 0.82 | MTOR (0.38) | CACNA1BVDRMTNR1AMTNR1BCNR1 | |
| SCHEMBL20004234 | 0.81 | SMN1; SMN2 (0.39) | NOD2NOD1 | |
| SCHEMBL20004834 | 0.78 | EPHX2 (0.43) | EPHX2NR1H4RXRARXRB | |
| SCHEMBL28351117 | 0.75 | MGAM (0.37) | — | |
| SCHEMBL28354748 | 0.74 | SLC6A3 (0.35) | NR1H4MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL18814851 | 0.73 | NPC1 (0.42) | MTNR1AMTNR1B | |
| SCHEMBL28351162 | 0.72 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL17434660 | 0.68 | ESR1 (0.34) | EPHX2VDRNR1H4RXRARXRB | |
| SCHEMBL29962699 | 0.68 | ESR1 (0.34) | EPHX2VDRNR1H4RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848361-A1 | METHOD OF PRODUCING TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-07-14 | — | — | EP | disclosed |