⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23639919 | 0.88 | KCNH2 (0.33) | — | |
| SCHEMBL22006103 | 0.80 | KCNH2 (0.33) | — | |
| SCHEMBL22536043 | 0.77 | — | — | |
| SCHEMBL18677383 | 0.75 | — | — | |
| SCHEMBL19958994 | 0.70 | KCNH2 (0.35) | — | |
| SCHEMBL20234525 | 0.69 | SLC6A1 (0.33) | — | |
| SCHEMBL19963605 | 0.69 | SLC6A1 (0.33) | — | |
| SCHEMBL22536243 | 0.69 | KCNH2 (0.31) | — | |
| SCHEMBL21941240 | 0.68 | GNAO1 (0.47) | — | |
| SCHEMBL19959055 | 0.67 | KCNH2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210213012-A1 | COMBINATIONS OF ESTROGEN RECEPTOR DEGRADERS AND CYCLIN-DEPENDENT KINASE INHIBITORS FOR TREATING CANCER | ACCUTAR BIOTECHNOLOGY INC. | 2021-07-15 | — | — | US | disclosed |