Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911979 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL5341628 | 0.81 | CYP2A6 (0.56) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3914588 | 0.80 | KDM4E (0.69) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23640291 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL31026601 | 0.80 | CYP2A6 (0.56) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23634920 | 0.80 | DYRK1A (0.69) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29001886 | 0.79 | CYP2A6 (0.76) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30450765 | 0.79 | CYP2A6 (0.76) | CYP2A6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23640303 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL23640323 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |