Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640291 | 0.84 | KDM4E (0.67) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL2761833 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL29716542 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL23640303 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL23640512 | 0.81 | PIM1 (0.64) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL2761829 | 0.79 | CA12 (0.66) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL2492142 | 0.78 | PIM1 (0.64) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL31621885 | 0.78 | PIM1 (0.64) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL23640290 | 0.78 | CYP2A6 (0.59) | ALDH1A1KMT2AKDM4ECA12CA9 | |
| SCHEMBL23640312 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848367-A1 | TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-07-14 | — | — | EP | disclosed |