Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.45 |
| ▸ | SKP1 | P63208 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943889 | 1.00 | GPR119 (0.48) | GPR119ACHEWNT3ACKS1BSKP1 | |
| SCHEMBL23630514 | 0.85 | ALDH1A1 (0.46) | HRH3KMT2ASMN1; SMN2AOC3 | |
| SCHEMBL23630504 | 0.80 | AOC3 (0.60) | HRH3MEN1KMT2AAOC3 | |
| SCHEMBL15228419 | 0.79 | GPR119 (0.56) | GPR119ACHECKS1BSKP1SKP2 | |
| Hydrochloric Acid SCHEMBL29943877 | 0.79 | AOC3 (0.59) | HRH3MEN1KMT2AAOC3 | |
| SCHEMBL20938625 | 0.79 | HRH3 (0.59) | GPR119ACHEWNT3ACKS1BSKP1 | |
| Hydrochloric Acid SCHEMBL23630339 | 0.79 | AOC3 (0.59) | HRH3MEN1KMT2AAOC3 | |
| SCHEMBL30546118 | 0.78 | HRH3 (0.57) | GPR119ACHECKS1BSKP1SKP2 | |
| SCHEMBL5682996 | 0.78 | HRH3 (0.57) | GPR119ACHECKS1BSKP1SKP2 | |
| SCHEMBL113805 | 0.78 | GPR119 (0.55) | GPR119ACHEWNT3ACKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021142247-A1 | SMARCA2-VHL DEGRADERS | AMGEN INC. (US) | 2021-07-15 | — | — | WO | disclosed |