SCHEMBL23640904

SCHEMBL23640904

CC1=CCCC(C)=C1c1ccccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 3/20 0.34
NPC1 O15118 2/20 0.34
GAA P10253 2/20 0.34
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
BRD4 O60885 3/20 0.33
IDO1 P14902 1/20 0.33
TSHR P16473 1/20 0.31
PIK3CA P42336 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79391 0.81 ALDH1A1 (0.44) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL79135 0.73 BRD4 (0.43) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL22562268 0.72 ALDH1A1 (0.39) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL22298316 0.72 ALDH1A1 (0.46) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL20860342 0.70 CYP3A4 (0.37) ALDH1A1HSD17B10CYP3A4TDP1MEN1
SCHEMBL21118267 0.69 MAOA (0.41) ALDH1A1HSD17B10KDM4ENPC1CYP3A4
SCHEMBL20860412 0.68 ALDH1A1 (0.41) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL79791 0.66 ALDH1A1 (0.43) ALDH1A1L3MBTL1HSD17B10KDM4ENPC1
SCHEMBL14101451 0.65
SCHEMBL2874924 0.65 CES1 (0.43) L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663308-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-07-14 EP disclosed