Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.62 |
| ▸ | EHMT1 | Q9H9B1 | 7/20 | 0.62 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477073 | 0.83 | EHMT2 (0.58) | EHMT2EHMT1IGF1RMAPTEGFR | |
| SCHEMBL19700619 | 0.83 | EHMT2 (0.71) | EHMT2EHMT1IGF1RMAPTEGFR | |
| SCHEMBL19462455 | 0.82 | EHMT2 (0.59) | EHMT2EHMT1IGF1RMAPTEGFR | |
| SCHEMBL19477065 | 0.82 | EHMT2 (0.61) | EHMT2EHMT1IGF1RMAPTEGFR | |
| SCHEMBL19476637 | 0.80 | EHMT2 (0.69) | EHMT2EHMT1IGF1RMAPTEGFR | |
| SCHEMBL19476364 | 0.79 | EHMT2 (0.71) | EHMT2EHMT1IGF1REGFRFGFR2 | |
| SCHEMBL19462272 | 0.78 | EHMT2 (0.59) | EHMT2EHMT1IGF1REGFRFGFR2 | |
| SCHEMBL19476628 | 0.78 | EHMT2 (0.59) | EHMT2EHMT1IGF1REGFRFGFR2 | |
| SCHEMBL19477364 | 0.78 | EHMT2 (0.63) | EHMT2EHMT1IGF1REGFRFGFR2 | |
| SCHEMBL19477260 | 0.78 | EHMT2 (0.69) | EHMT2EHMT1IGF1REGFRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210213014-A1 | METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES | Epizyme, Inc. | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213014-A1 | METHODS OF USING EHMT2 INHIBITORS IN IMMUNOTHERAPIES | EHMT2, BHMT2, BHMT | EHMT2 1/4885EHMT1 4/4885IGF1R 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.