Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243061 | 1.00 | TDP1 (0.38) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL24780887 | 0.89 | ALDH1A1 (0.34) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL3144118 | 0.87 | TDP1 (0.35) | TDP1KMT2AMEN1GAACA1 | |
| SCHEMBL24669226 | 0.87 | TDP1 (0.39) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL15343533 | 0.87 | TDP1 (0.39) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL14598292 | 0.85 | TDP1 (0.37) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL24669269 | 0.84 | TDP1 (0.44) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL20713800 | 0.84 | TDP1 (0.44) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL12292244 | 0.83 | TDP1 (0.36) | TDP1CTSKKMT2AMEN1GAA | |
| SCHEMBL9339358 | 0.83 | MEN1 (0.37) | TDP1CTSKKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| US-20210214356-A1 | COMPOUNDS AND MEDICAMENTS USING SAME | IRIMAJIRI THERAPEUTICS INC. (JP) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214356-A1 | COMPOUNDS AND MEDICAMENTS USING SAME | F12, GDI2, RDX | TDP1 3152/4885CTSK 2186/4885KMT2A 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.