Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954295 | 0.98 | ALDH1A1 (0.75) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL21814409 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1KMT2ALMNA | |
| SCHEMBL23631273 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL23643554 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL7634923 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL3439041 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL15708326 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| E1501 SCHEMBL28165541 | 0.85 | ALDH1A1 (0.92) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL3439060 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL11273000 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | KDR, RB1, PDE6C | ALDH1A1 2125/4885MAPK1 785/4885L3MBTL1 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.